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Research library

Explore selected publications, evidence types, key findings, and registered studies with direct links to each primary record. This curated library is not a complete archive of the thousands of studies across the wider scientific literature.

PublicationsClinical trials

20 publications

Showing records relevant to Thymalin.

Human clinical

Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.

Key finding

In human hematopoietic stem-cell cultures, Thymalin reduced immature-cell markers and increased the mature T-cell marker CD28 by 6.8-fold.

Bulletin of experimental biology and medicine 2020

Direct Thymalin human-cell differentiation evidence. Relevant to Thymalin

PubMed
Review

[Geroprotective effect of thymalin and epithalamin].

Key finding

A 6-to-8-year clinical follow-up of 266 older adults associated Thymalin and Epithalamin use with improved physiological measures and lower respiratory-disease incidence and mortality than controls.

Advances in gerontology = Uspekhi gerontologii 2002

Direct Thymalin long-term clinical evidence. Relevant to Thymalin

PubMed
Human clinical

Reparative osteogenesis in mandible in cases of filling a bone defect with hydroxyapatite-containing osteotropic material and injecting the surrounding soft tissues with thymalin: experimental and morphological study.

Key finding

In a rat mandibular-defect model, local Thymalin alongside a hydroxyapatite graft accelerated tissue clearance, osteoblast activity and bone mineralization.

Wiadomosci lekarskie (Warsaw, Poland : 1960) 2024

Direct Thymalin animal bone-repair evidence. Relevant to Thymalin

PubMed
Human clinical

[Effectiveness of administration of thymalin in the complex treatment of pulmonary tuberculosis].

Key finding

In a 60-patient pulmonary-tuberculosis report, adding Thymalin to chemotherapy was associated with shorter hospitalization, stronger immune recovery and improved treatment response.

Problemy tuberkuleza 1990

Direct Thymalin human clinical report. Relevant to Thymalin

PubMed
Human clinical

The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.

Key finding

Human-cell and molecular-modelling experiments linked Thymalin's KE and EW dipeptides to regulation of inflammatory gene expression and protein synthesis.

International journal of molecular sciences 2023

Thymalin dipeptide human-cell mechanism evidence. Relevant to Thymalin

PubMed
Human clinical

[Thymalin in the treatment of patients with erysipelas].

Key finding

This publication reports research findings relevant to [thymalin in the treatment of patients with erysipelas].

Klinicheskaia meditsina 1987

Direct Thymalin evidence. Relevant to Thymalin

PubMed
Human clinical

[Effectiveness of thymalin and prodigiozan in the complex treatment of patients with dysentery].

Key finding

This publication reports research findings relevant to [effectiveness of thymalin and prodigiozan in the complex treatment of patients with dysentery].

Voenno-meditsinskii zhurnal 1985

Direct Thymalin evidence. Relevant to Thymalin

PubMed
Human clinical

[Morphological compound and indicators of the blood clotting system in severe COVID-19 patients of middle aged and elderly during treatment of Tocilizumab and Thymalin.].

Key finding

The study reports that thymain decreased the platelet/lymphocyte and neutrophil/lymphocyte ratios by 1,4 times and 2 times.

Advances in gerontology = Uspekhi gerontologii 2022

Direct Thymalin evidence. Relevant to Thymalin

PubMed
Human clinical

[Thymalin in the combined treatment of parkinsonism patients].

Key finding

The study reports that efficacy of thymolin use is confirmed by EEG mapping; there has been established a significant decrement in the power of alpha rhythm in the anterocentral regions of the brain, which fact suggests to us an improvement in the cortical neurodynamics.

Likars'ka sprava 1999

Direct Thymalin evidence. Relevant to Thymalin

PubMed
Human clinical

[Use of thymic peptide thymalin in the complex treatment of therapy-resistant schizophrenia].

Key finding

The study reports that such a policy favoured considerable enhancement of the treatment efficacy which manifested itself by the elimination or amelioration of psychic disorders, appreciable activation of patients and reduction of neuroleptic complications.

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) 1990

Direct Thymalin evidence. Relevant to Thymalin

PubMed
Human clinical

[Experimental and clinical study of a new immunoregulator preparation thymalin].

Key finding

This publication reports research findings relevant to [experimental and clinical study of a new immunoregulator preparation thymalin].

Voenno-meditsinskii zhurnal 1982

Direct Thymalin evidence. Relevant to Thymalin

PubMed
Human clinical

[The application efficacy of immunomodulators in complex of treatment of an acute necrotic pancreatitis].

Key finding

The study reports that analysis of efficacy of the immunomodulators application, thymalin in particular, in complex treatment algorhythm in 18 patients with an acute necrotic pancreatitis was conducted.

Klinichna khirurhiia 2004

Research relevant to Thymalin. Relevant to Thymalin

PubMed
Human clinical

[Immunotherapy in the combined treatment of chronic destructive pulmonary tuberculosis].

Key finding

The study reports that the patients with fibrous and cavernous tuberculosis display a combination of antituberculous antibody hyperproduction and specific cell-mediated response inhibition.

Problemy tuberkuleza 1994

Research relevant to Thymalin. Relevant to Thymalin

PubMed
Human randomized

Peptides of pineal gland and thymus prolong human life.

Key finding

The obtained data confirmed the high geroprotective efficacy of Thymalin and Epithalamin and the expediency of their application in medicine and social care for health maintenance and age-related pathology prevention in persons over 60 to prolong their active longevity.

Neuro endocrinology letters 2003

Relevant to Thymalin

PubMed
Human clinical

Chrono- and Immunocorrection of Inflammatory Disorders of Internal Reproductive Organs in Women of Reproductive Age.

Key finding

The study reports that the timing of the presence of SDH reaction to drugs in the immunocompetent cells makes it possible to set the optimal daily regime of their application and to select a drug that would be most effective in each particular case.

Bulletin of experimental biology and medicine 2015

Research relevant to Thymalin. Relevant to Thymalin

PubMed
Human clinical

[Prevention of postoperative complications in diffuse purulent peritonitis in children].

Key finding

The study reports that with the use of this complex the results of treatment were significantly improved in 21 children and the number of complications was much less than in the control group of patients subjected to operation.

Khirurgiia 1994

Research relevant to Thymalin. Relevant to Thymalin

PubMed
Human clinical

[Differentiated immunocorrective therapy in nonspecific ulcerative colitis].

Key finding

The study reports that corticosteroids were more effective in inflammatory-destructive changes in the mucosa of the large intestine while in mild inflammation with prevalence of ulcerative-reparative processes, immunomodulators (thymalin) are preferred.

Likars'ka sprava 1992

Research relevant to Thymalin. Relevant to Thymalin

PubMed
Observational

Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line.

Key finding

These peptides (Khavinson Peptides®), characterized by Prof.

International journal of molecular sciences 2022

Relevant to Thymalin

PubMed
Review

Peptides and Ageing.

Key finding

A technology has been developed for manufacturing of biologically active complex peptide preparations from extracts of different tissues.

Neuro endocrinology letters 2002

Relevant to Thymalin

PubMed
Review

Chornobyl catastrophe: cytogenetic effects of low dose ionizing radiation and their modification.

Key finding

The study reports that this article is part of a Special Issue entitled "The Chornobyl Nuclear Accident: Thirty Years After".

Experimental oncology 2016

Research relevant to Thymalin. Relevant to Thymalin

PubMed

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