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Research library

Explore selected publications, evidence types, key findings, and registered studies with direct links to each primary record. This curated library is not a complete archive of the thousands of studies across the wider scientific literature.

PublicationsClinical trials

14 publications

Showing records relevant to Thymogen.

Human clinical

[The effect of thymogen on the state of immunity in destructive pulmonary tuberculosis].

Key finding

The study reports that it recommends 2 courses of timoguen immunostimulation (1% solution by 1 ml injection N 10 in 2 days for 2 and 4 mouths' treatment course).

Voenno-meditsinskii zhurnal 1999

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Preclinical animal

Hepatoprotective Effects of Thymogen Analogues in Hydrazine Hepatopathy in Rats.

Key finding

The study reports that thymogen analogue with D-Ala at the C-terminus was most effective.

Bulletin of experimental biology and medicine 2025

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Preclinical animal

[The effect of the synthetic immunomodulator thymogen on radiation-induced carcinogenesis in rats].

Key finding

The study reports that radionuclide-treated rats showed higher occurrence of tumors on the whole and of breast adenocarcinoma, in particular.

Voprosy onkologii 1992

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Published research

Reparative and Antioxidant Effects of New Analogues of Immunomodulator Thymogen in Experimental Model of Liver Damage.

Key finding

The study reports that inclusion of D-Ala enhanced the effect of Thymogen on the processes of regeneration in hepatocytes and the antioxidant effect under conditions of acute carbon tetrachloride hepatopathy.

Bulletin of experimental biology and medicine 2023

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Human randomized

[Application thymogen for preoperative preparation of elderly patients with tumor processes in abdominal cavity].

Key finding

The study reports that a double-blind, randomized, placebo-controlled study of the efficacy of Thymogen preparation for elderly patients for surgery on the solid tumors in abdominal cavity and retroperitoneal space was carried out.

Advances in gerontology = Uspekhi gerontologii 2011

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Human clinical

[Changes of immune and non-specific reactivity in patients with chronic suppurative obstructive bronchitis in comprehensive treatment with thymogen].

Key finding

The study reports that the use of thymogen in multi-modality treatment contributed to normalization of T-cell immunity (increases in E-rosette formation, responses of blast cell transformation to phytohemagglutinin, Tx/Tc ratio), as well as nonspecific responsiveness parameters (C3c, NBT-test, natural killers), resulting in higher clinical efficacy.

Problemy tuberkuleza 1994

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Human clinical

[Thymogen in the complex treatment of inflammatory diseases of the female genital system].

Key finding

The study reports that the drug is characterized by a desensitizing effect and induces no complications.

Akusherstvo i ginekologiia 1992

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Preclinical animal

[Use of thymogen in the treatment of various forms of acute abdominal disorders in an experiment].

Key finding

The study reports that in the experimental group less pronounced depression of antiradical activity (superoxide dismutase and catalase activity control) was found, leukocytosis and leukocyte intoxication index were diminished.

Patologicheskaia fiziologiia i eksperimental'naia terapiia 1998

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Review

The First Reciprocal Activities of Chiral Peptide Pharmaceuticals: Thymogen and Thymodepressin, as Examples.

Key finding

The study reports that the selected clinical result will be discussed.

International journal of molecular sciences 2024

Direct Thymogen evidence. Relevant to Thymogen

PubMed
Human randomized

[Repair stimulator alpha-glutamyl-tryptophan in the complex therapy of chronic atrophic gastritis: results of histological examination].

Key finding

The study reports that a statistically significant positive effect of the study drug on regenerative mechanisms leading to stabilization and/or improvement of the histological picture in the atrophic area of the gastric mucosa was found in comparison with the control of the initial state and with placebo.

Arkhiv patologii 2023

Research relevant to Thymogen. Relevant to Thymogen

PubMed
Human randomized

[Endoscopic and morphometric analysis of the reduction of acute inflammatory process in the gastric mucosa after therapy with Regasthym Gastro].

Key finding

The study reports that regasthym Gastro contributes to a significant decrease in the severity of the inflammatory process according to the evaluation of the results of gastroscopy and morphometry.

Terapevticheskii arkhiv 2023

Research relevant to Thymogen. Relevant to Thymogen

PubMed
Human clinical

[Applications of immunomodulators in complex of treatment of the soft tissue purulent wounds].

Key finding

The study reports that in 31 patients with purulent wound of soft tissues more rapid cleansing and healing of the wound, the immunity indexes normalization were noted while application of immunomodulator thymogen in combination with the siliceous sorbent sillard application and adaptogenic preparation--tincture of Echinacea Purpurea.

Klinichna khirurhiia 2000

Research relevant to Thymogen. Relevant to Thymogen

PubMed
Preclinical animal

BEHAVIORAL AND NEUROCHEMICAL CHANGES DURING INTRANASAL ADMINISTRATION OF ALPHA-GLUTAMYL-TRYPTOPHAN AND CHELATE COMPLEX OF ZINC ARGINYL-GLYCINATE ON MONOAMINE SYSTEMS DYSFUNCTIONS KNOCK-OUT MODELS.

Key finding

The study reports that thus, these data indicate that intranasal delivery of the dipeptides is effective during acute and chronic intranasal administration in rodents, the latter showed a change in the anxiety indicator.

Georgian medical news 2024

Research relevant to Thymogen. Relevant to Thymogen

PubMed
Laboratory study

The Effect of Drugs with α-Glutamyl-Tryptophan for Cytokine Secretion and Level of Surface Molecule ICAM-1 In Vitro.

Key finding

The study reports that at the same time, the drug reduced secretion of the IL-8 cytokine induced by TNFα and increased the spontaneous level of ICAM-1 in mononuclear cells.

Cell and tissue biology 2023

Research relevant to Thymogen. Relevant to Thymogen

PubMed

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