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Research library

Explore selected publications, evidence types, key findings, and registered studies with direct links to each primary record. This curated library is not a complete archive of the thousands of studies across the wider scientific literature.

PublicationsClinical trials

8 publications

Showing records relevant to NK Peptide.

Review

Peptide-specific natural killer cell receptors.

Key finding

The review identifies natural-killer-cell receptors that recognize specific HLA-presented peptide sequences and explains how this selectivity can support pathogen surveillance.

Oxford open immunology 2025

Peptide-specific NK-receptor evidence review. Relevant to NK Peptide

PubMed
Published research

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation.

Key finding

A high-throughput HLA-E screen identified 500 candidate peptides, including ligands that selectively activated NKG2C-positive natural killer cells.

Nature communications 2023

NK-activating peptide discovery evidence. Relevant to NK Peptide

PubMed
Published research

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.

Key finding

Distinct cytomegalovirus UL40 peptides controlled expansion and differentiation of adaptive NKG2C-positive natural killer-cell populations.

Nature immunology 2018

Human peptide-specific adaptive NK evidence. Relevant to NK Peptide

PubMed
Review

Effects of Peptide on NK cell-mediated MHC I recognition.

Key finding

This review shows that inhibitory and activating NK receptors can distinguish peptide motifs within MHC-I complexes, altering the balance of NK-cell activation and inhibition.

Frontiers in immunology 2014

Peptide-dependent NK-recognition review. Relevant to NK Peptide

PubMed
Review

NK cells: tuned by peptide?

Key finding

The review describes how HLA-bound peptides tune KIR and CD94:NKG2 receptor signalling, allowing natural killer cells to sense changes in cellular peptide repertoires.

Immunological reviews 2015

Peptide-tuned NK-signalling review. Relevant to NK Peptide

PubMed
Preclinical animal

Natural Killer Cell Education in Women With Recurrent Pregnancy Loss.

Key finding

The study reports that rPL women with the HLA-B T/T variant had a lower percentage of NKG2A-educated NK cells (47.8%) compared to controls (66.4%) (p = 0.025).

American journal of reproductive immunology (New York, N.Y. : 1989) 2025

Research relevant to NK Peptide. Relevant to NK Peptide

PubMed
Laboratory study

Anti-MSLN chimeric antigen receptor-like NK cell therapy with tumor-penetrating capacity (uCAR-like NK) for solid tumors.

Key finding

The study reports that overall, this study establishes a modular, nongenetically engineered uCAR-like NK platform that couples targeted recognition with enhanced tissue access.

Signal transduction and targeted therapy 2025

Research relevant to NK Peptide. Relevant to NK Peptide

PubMed
Published research

A vaccine targeting resistant tumours by dual T cell plus NK cell attack.

Key finding

The study reports that notably, this vaccine maintains efficacy against MHC class I-deficient tumours resistant to cytotoxic T cells through the coordinated action of NK cells and CD4+ T cells.

Nature 2022

Research relevant to NK Peptide. Relevant to NK Peptide

PubMed

This library supports source-led professional evaluation. Product-specific clinical and regulatory guidance provides the framework for interpreting the records in context.

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