Skip to main content
Labbieux
Back to NAD 600+

Research library

Explore selected publications, evidence types, key findings, and registered studies with direct links to each primary record. This curated library is not a complete archive of the thousands of studies across the wider scientific literature.

PublicationsClinical trials

8 publications

Showing records relevant to NAD 600+.

Review

Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.

Key finding

The study reports that increased synthesis of NAD+ promotes protective cell responses, further demonstrating that NAD+ is a regulatory molecule associated with several biochemical pathways.

Antioxidants & redox signaling 2019

Component evidence for NAD+. Relevant to NAD 600+

PubMed
Review

Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions.

Key finding

The study reports that advancing age and many disease states are associated with declines in nicotinamide adenine dinucleotide (NAD+) levels.

The journals of gerontology. Series A, Biological sciences and medical sciences 2023

Direct NAD+ evidence. Relevant to NAD 600+

PubMed
Review

NAD+ metabolism and its roles in cellular processes during ageing.

Key finding

The study reports that many of these ageing-associated diseases can be slowed down and even reversed by restoring NAD+ levels.

Nature reviews. Molecular cell biology 2021

Direct NAD+ evidence. Relevant to NAD 600+

PubMed
Review

Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns.

Key finding

The study reports that we suggest that these early findings provide the rationale for adequately powered randomized trials to evaluate the efficacy of NAD+ augmentation as a therapeutic strategy to prevent and treat metabolic disorders and age-related conditions.

Endocrine reviews 2023

Component evidence for NAD+. Relevant to NAD 600+

PubMed
Review

NAD⁺ in aging, metabolism, and neurodegeneration.

Key finding

The study reports that here we review factors that regulate NAD(+) and discuss how supplementation with NAD(+) precursors may represent a new therapeutic opportunity for aging and its associated disorders, particularly neurodegenerative diseases.

Science (New York, N.Y.) 2015

Component evidence for NAD+. Relevant to NAD 600+

PubMed
Review

NAD+ and sirtuins in aging and disease.

Key finding

The study reports that thus, the combination of sirtuin activation and NAD(+) intermediate supplementation may be an effective antiaging intervention, providing hope to aging societies worldwide.

Trends in cell biology 2014

Direct NAD+ evidence. Relevant to NAD 600+

PubMed
Review

The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.

Key finding

The study reports that as the NAD+ concentration in human skin, blood, liver, muscle, and brain are thought to decrease with age, finding ways to increase NAD+ status could possibly influence the aging process and associated metabolic sequelae.

Advances in nutrition (Bethesda, Md.) 2023

Component evidence for NAD+. Relevant to NAD 600+

PubMed
Human randomized

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects.

Key finding

12 wk of NR supplementation in doses of 2000 mg/d appears safe, but does not improve insulin sensitivity and whole-body glucose metabolism in obese, insulin-resistant men.

The American journal of clinical nutrition 2018

Relevant to NAD 600+

PubMed

This library supports source-led professional evaluation. Product-specific clinical and regulatory guidance provides the framework for interpreting the records in context.

Browse all products