Skip to main content
Labbieux
Back to Exosomes

Research library

Explore selected publications, evidence types, key findings, and registered studies with direct links to each primary record. This curated library is not a complete archive of the thousands of studies across the wider scientific literature.

PublicationsClinical trials

22 publications

Showing records relevant to Exosomes.

Review

Advances in microRNA from adipose-derived mesenchymal stem cell-derived exosome: focusing on wound healing.

Key finding

The study reports that this paper describes the application and mechanism whereby ADMSC-Exo-miRNA regulates wound healing.

Journal of materials chemistry. B 2022

Research relevant to Exosomes. Relevant to Exosomes

PubMed
Review

Exosomes from adipose-derived stem cells and application to skin wound healing.

Key finding

The study reports that compared with ADSCs therapeutics, ADSCs-EXOs have highly stability and are easily stored.

Cell proliferation 2021

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Preclinical animal

Human Umbilical Cord Mesenchymal Stem Cells Derived Exosomes Improved The Aged Mouse IVM Oocytes Quality.

Key finding

The study reports that we found the quality of oocytes was improved by HUCMSCs-exosomes.

Reproductive sciences (Thousand Oaks, Calif.) 2024

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Preclinical animal

Melatonin improves therapeutic potential of mesenchymal stem cells-derived exosomes against renal ischemia-reperfusion injury in rats.

Key finding

The study reports that this study tested the hypothesis that administration of exosomes derived from MSCs preconditioned with Mel gave best protection against RIRI as compared to therapy by MSCs or exosomes derived from non-preconditioned MSCs.

American journal of translational research 2019

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Preclinical animal

Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis.

Key finding

The study reports that furthermore, the chemoattractive effects of CCL2 and CCL21 on inflammatory cells were inhibited by MSC-Exo.

Scientific reports 2017

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Human clinical

Exosomes from adipose-derived stem cells inhibits skin cancer progression via miR-199a-5p/SOX4.

Key finding

The study reports that miR-199a-5p inhibitor enhanced cell viability and invasion.

Biotechnology & genetic engineering reviews 2024

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Preclinical animal

Exosomes derived from MSCs ameliorate retinal laser injury partially by inhibition of MCP-1.

Key finding

The study reports that both MSCs and their exosomes reduced damage, inhibited apoptosis, and suppressed inflammatory responses to obtain better visual function to nearly the same extent in vivo.

Scientific reports 2016

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Review

Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration.

Key finding

The study reports that this review highlights recent studies that investigate therapeutic potential of MSC-exosomes and relevant mode of actions for skin diseases, as well as quality control measures required for development of exosome-derived therapeutics.

Cells 2020

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Published research

Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis.

Key finding

The study reports that atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation.

Cells 2020

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Human clinical

Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging.

Key finding

The study reports that 3D HDF-XOs caused increased procollagen type I expression and a significant decrease in MMP-1 expression, mainly through the downregulation of tumor necrosis factor-alpha (TNF-α) and the upregulation of transforming growth factor beta (TGF-β).

ACS nano 2019

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Preclinical animal

Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth.

Key finding

The study reports that intra-tumor injection of exosomes derived from miR-146-expressing MSCs significantly reduced glioma xenograft growth in a rat model of primary brain tumor.

Cancer letters 2013

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Review

Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine.

Key finding

The study reports that overall, this review highlights the burgeoning roles and potential applications of exosomes in regenerative medicine.

Cells 2021

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Review

Exosomes derived from mesenchymal stem cells.

Key finding

The study reports that compared with cells, exosomes are more stable and reservable, have no risk of aneuploidy, a lower possibility of immune rejection following in vivo allogeneic administration, and may provide an alternative therapy for various diseases.

International journal of molecular sciences 2014

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Review

Exosomes/miRNAs as mediating cell-based therapy of stroke.

Key finding

The study reports that the release as well as the content of the MSC generated exosomes are modified by environmental conditions.

Frontiers in cellular neuroscience 2014

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Review

Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery.

Key finding

The study reports that its exosomes are therapeutic in animal model of disease and exhibit immunosuppressive activity.

Advanced drug delivery reviews 2013

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Published research

Topical moisturizer with rose stem cell-derived exosomes (RSCEs) for recalcitrant seborrheic dermatitis: A case report with 6 months of follow-up.

Key finding

The study reports that this demonstrated not only the efficacy of RSCEs in symptom management but also their potential in extending remission periods.

Journal of cosmetic dermatology 2024

Direct Exosomes evidence. Relevant to Exosomes

PubMed
Human clinical

Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression.

Key finding

The study reports that improved neurological impairment and long-term neuroprotection associated with enhanced angioneurogenesis were noticed in stroke mice receiving EVs from two different bone marrow-derived MSC lineages.

Stem cells translational medicine 2015

Research relevant to Exosomes. Relevant to Exosomes

PubMed
Preclinical animal

TSG6-Exo@CS/GP Attenuates Endometrium Fibrosis by Inhibiting Macrophage Activation in a Murine IUA Model.

Key finding

The study reports that unfortunately, severe cases of IUA currently lack effective treatments.

Advanced materials (Deerfield Beach, Fla.) 2024

Research relevant to Exosomes. Relevant to Exosomes

PubMed
Preclinical animal

MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles.

Key finding

The study reports that the outcomes were significantly enhanced with miR-133b(+) MSC treatment, and were significantly decreased with miR-133b(-) MSC treatment, compared to naïve MSC treatment.

Stem cells (Dayton, Ohio) 2013

Research relevant to Exosomes. Relevant to Exosomes

PubMed
Human clinical

An Exosome-based Transcriptomic Signature for Noninvasive, Early Detection of Patients With Pancreatic Ductal Adenocarcinoma: A Multicenter Cohort Study.

Key finding

The study reports that furthermore, this transcriptomic signature successfully identified CA19-9 negative cases (<37 U/mL; AUC = 0.96), when analyzed in combination with CA19-9 levels, significantly improved the overall diagnostic accuracy (AUC = 0.99 vs AUC = 0.86 for CA19-9 alone).

Gastroenterology 2022

Research relevant to Exosomes. Relevant to Exosomes

PubMed

This library supports source-led professional evaluation. Product-specific clinical and regulatory guidance provides the framework for interpreting the records in context.

Browse all products