VIP

Tipo de evidência

Revisão científica

Direct or closely related VIP evidence

Publicação e principal conclusão

Immunoeffector and immunoregulatory activities of vasoactive intestinal peptide.

Vasoactive intestinal peptide (VIP) and its two G protein-coupled receptors, VPAC1R and VPAC2R, are prominent in the immune system and potently affect T cells and macrophages.

Regulatory peptides

Fonte

PMID 12409234 · 2002

Tipo de evidência

Revisão científica

Direct or closely related VIP evidence

Publicação e principal conclusão

VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins.

The vasoactive intestinal peptide (VIP) is a neuropeptide with wide distribution in both central and peripheral nervous systems, where it plays important regulatory role in many physiological processes.

British journal of pharmacology

Fonte

PMID 21951273 · 2012

Tipo de evidência

Estudo pré-clínico

VIP mechanism or target context

Publicação e principal conclusão

Polypeptide with broad biological activity: isolation from small intestine.

A polypeptide, which has potent and diverse biological action-including systemic vasodilation, hypotension, increased cardiac output, respiratory stimulation, and hyperglycemia-was isolated from the small intestine of the hog.

Science (New York, N.Y.)

Fonte

PMID 5450698 · 1970

Tipo de evidência

Revisão científica

Direct or closely related VIP evidence

Publicação e principal conclusão

Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions.

Vasoactive intestinal peptide (VIP), a 28-amino acid neuropeptide/neurotransmitter, is widely distributed in both the central and peripheral nervous system.

Amino acids

Fonte

PMID 22139413 · 2011