Vrsta dokaza
Opservacijsko istraživanje
Direct or closely related Humanin evidence
Publikacija i ključni nalaz
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.
Through functional expression screening, we identified a gene, designated Humanin (HN) cDNA, which encodes a short polypeptide and abolishes death of neuronal cells caused by multiple different types of familial Alzheimer's disease genes and by Abeta amyloid, without effect on death by Q79 or superoxide dismutase-1 mutants.
Proceedings of the National Academy of Sciences of the United States of America