NAD Spray

Tipo de evidencia

Estudio preclínico

Research relevant to NAD Spray

Publicación y hallazgo principal

Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotide.

The study reports that in addition, delayed microglial activation normally seen after TBI was reduced by NAD⁺ treatment at 7 days after insult.

Journal of neurotrauma

Fuente

PMID 22352983 · 2012

Tipo de evidencia

Estudio preclínico

Direct NAD Spray evidence

Publicación y hallazgo principal

Intranasal administration with NAD+ profoundly decreases brain injury in a rat model of transient focal ischemia.

The study reports that the NAD+ administration also significantly attenuated ischemia-induced neurological deficits.

Frontiers in bioscience : a journal and virtual library

Fuente

PMID 17127275 · 2007

Tipo de evidencia

Revisión científica

Direct NAD Spray evidence

Publicación y hallazgo principal

Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions.

The study reports that advancing age and many disease states are associated with declines in nicotinamide adenine dinucleotide (NAD+) levels.

The journals of gerontology. Series A, Biological sciences and medical sciences

Fuente

PMID 37068054 · 2023

Tipo de evidencia

Revisión científica

Direct NAD Spray evidence

Publicación y hallazgo principal

NAD+ metabolism and its roles in cellular processes during ageing.

The study reports that many of these ageing-associated diseases can be slowed down and even reversed by restoring NAD+ levels.

Nature reviews. Molecular cell biology

Fuente

PMID 33353981 · 2021